miR-22 represses cancer progression by inducing cellular senescence

Cellular senescence acts as a barrier to cancer progression, and microRNAs (miRNAs) are thought to be potential senescence regulators. However, whether senescence-associated miRNAs (SA-miRNAs) contribute to tumor suppression remains unknown. Here, we report that miR-22, a novel SA-miRNA, has an impa...

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Detalhes bibliográficos
Main Authors: Xu, Dan, Takeshita, Fumitaka, Hino, Yumiko, Fukunaga, Saori, Kudo, Yasusei, Tamaki, Aya, Matsunaga, Junko, Takahashi, Ryou-u, Takata, Takashi, Shimamoto, Akira, Ochiya, Takahiro, Tahara, Hidetoshi
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080260/
https://ncbi.nlm.nih.gov/pubmed/21502362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201010100
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