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Crystallization and preliminary X-ray crystallographic studies of the CIDE-domain complex between Drep2 and Drep3 from Drosophila melanogaster

The DFF40–DFF45 heterodimeric complex is a primary player in apoptotic DNA fragmentation and is conserved among different species including Drosophila melanogaster. DFF40 is a novel nuclease, while DFF45 is an inhibitor that can suppress the nuclease activity of DFF40 via tight interaction. Unlike m...

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Bibliografski detalji
Glavni autori: Park, Ok Kyeung, Park, Hyun Ho
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080149/
https://ncbi.nlm.nih.gov/pubmed/21505240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111003113
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