Sensitivity to Low-Dose/Low-LET Ionizing Radiation in Mammalian Cells Harboring Mutations in Succinate Dehydrogenase Subunit C is Governed by Mitochondria-Derived Reactive Oxygen Species

It has been hypothesized that ionizing radiation-induced disruptions in mitochondrial O(2) metabolism lead to persistent heritable increases in steady-state levels of intracellular superoxide (O(2)(•−)) and hydrogen peroxide (H(2)O(2)) that contribute to the biological effects of radiation. Hamster...

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Bibliografische gegevens
Hoofdauteurs: Aykin-Burns, Nukhet, Slane, Benjamin G., Liu, Annie T. Y., Owens, Kjerstin M., O'Malley, Malinda S., Smith, Brian J., Domann, Frederick E., Spitz, Douglas R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080019/
https://ncbi.nlm.nih.gov/pubmed/21268708
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