The differences in the T2 relaxation rates of the protons in the partially-deuteriated and fully protonated sugar residues in a large oligo-DNA ('NMR-window') gives complementary structural information.

Selective incorporation of the stereospecifically deuteriated sugar moieties (> 97 atom % 2H enhancements at H2', H2'', H3' and H5'/5'' sites, approximately 85 atom % 2H enhancement at H4' and approximately 20 atom % 2H enhancement at H1') in DNA and RNA by the 'NMR-window' approach has been shown t...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Agback, P, Maltseva, T V, Yamakage, S I, Nilson, F P, Földesi, A, Chattopadhyaya, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1994
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307998/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8190632/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.8.1404
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