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Do Mice Habituate to “Gentle Handling?” A Comparison of Resting Behavior, Corticosterone Levels and Synaptic Function in Handled and Undisturbed C57BL/6J Mice

STUDY OBJECTIVES: “Gentle handling” has become a method of choice for 4-6 h sleep deprivation in mice, with repeated brief handling applied before sleep deprivation to induce habituation. To verify whether mice do indeed habituate, we assess how 6 days of repeated brief handling impact on resting be...

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Autors principals: Longordo, Fabio, Fan, Jing, Steimer, Thierry, Kopp, Caroline, Lüthi, Anita
Format: Artigo
Idioma:Inglês
Publicat: Associated Professional Sleep Societies, LLC 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079948/
https://ncbi.nlm.nih.gov/pubmed/21532962
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