Mutations to nonsense codons in human genetic disease: implications for gene therapy by nonsense suppressor tRNAs.
Nonsense suppressor tRNAs have been suggested as potential agents for human somatic gene therapy. Recent work from this laboratory has described significant effects of 3' codon context on the efficiency of human nonsense suppressors. A rapid increase in the number of reports of human diseases caused...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1994
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| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307985/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8190621/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.8.1327 |
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