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Clozapine and PD149163 Elevate Prepulse Inhibition in Brown Norway Rats

BACKGROUND: Unmedicated schizophrenia patients exhibit deficits in prepulse inhibition of the acoustic startle response (PPI). Similar deficits can be induced in rodents via a variety of manipulations and these deficits can be reversed by antipsychotics. Brown Norway (BN) rats exhibit natural PPI de...

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Detalhes bibliográficos
Main Authors: Feifel, David, Shilling, Paul D., Melendez, Gilia
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079344/
https://ncbi.nlm.nih.gov/pubmed/21463026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1037/a0022691
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