Characterization of the methylation patterns in human papillomavirus type 16 viral DNA in head and neck cancers

Human papillomavirus type 16 can integrate into the host genome, thereby rendering the viral coding genes susceptible to epigenetic modification. Using bisulfite genomic sequencing, we determined the methylation status of all 110 CpG sites within the viral epigenome in advanced stage III/IV HPV-16 a...

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Detalhes bibliográficos
Main Authors: Park, Il-Seok, Chang, Xiaofei, Loyo, Myriam, Wu, Gaosong, Chuang, Alice, Kim, Myoung Sook, Chae, Young Kwang, Lyford-Pike, Sofia, Westra, William H., Saunders, John R., Sidransky, David, Pai, Sara Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079312/
https://ncbi.nlm.nih.gov/pubmed/21292634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0147
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