Pharmacological inhibition of myostatin suppresses systemic inflammation and muscle atrophy in mice with chronic kidney disease

Chronic kidney disease (CKD) and several other catabolic conditions are characterized by increased circulating inflammatory cytokines, defects in IGF-1 signaling, abnormal muscle protein metabolism, and progressive muscle atrophy. In these conditions, no reliable treatments successfully block the de...

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Detalhes bibliográficos
Main Authors: Zhang, Liping, Rajan, Vik, Lin, Eugene, Hu, Zhaoyong, Han, H. Q., Zhou, Xiaolan, Song, Yanping, Min, Hosung, Wang, Xiaonan, Du, Jie, Mitch, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2011
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079306/
https://ncbi.nlm.nih.gov/pubmed/21282204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-176917
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