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Microdomain organization and frequency-dependence of CREB-dependent transcriptional signaling in heart cells

Voltage-gated Ca(v)1.2 calcium channels couple membrane depolarization to cAMP response-element-binding protein (CREB)-dependent transcriptional activation. To investigate the spatial and temporal organization of CREB-dependent transcriptional nuclear microdomains, we combined perforated patch-clamp...

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Detalhes bibliográficos
Main Authors: Kobrinsky, Evgeny, Duong, Son Q., Sheydina, Anna, Soldatov, Nikolai M.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079295/
https://ncbi.nlm.nih.gov/pubmed/21248242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-176198
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