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Tumor Hypoxia and Genetic Alterations in Sporadic Cancers

The cancer genome contains many gene alterations. How cancer cells acquire these alterations is a matter for discussion. One hypothesis is that cancer cells obtain mutations in genome stability genes at an early stage of tumor development, which results in genetic instability and generates a gene po...

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Detalhes bibliográficos
Main Authors: Koi, Minoru, Boland, C.R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079283/
https://ncbi.nlm.nih.gov/pubmed/21272156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1447-0756.2010.01377.x
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