The Oct-2 transcription factor represses tyrosine hydroxylase expression via a heptamer TAATGARAT-like motif in the gene promoter.

The tyrosine hydroxylase (TH) gene promoter contains adjacent octamer and heptamer motifs which act as target sites for octamer binding transcription factors. Mutation of the heptamer motif but not the octamer motif enhances TH promoter activity in neuronal cells expressing Oct-2 but not in non-expr...

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Bibliographic Details

Published in:	Nucleic Acids Res
Main Authors:	Dawson, S J, Yoon, S O, Chikaraishi, D M, Lillycrop, K A, Latchman, D S
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 1994
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307925/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7908738/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.6.1023
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