Apolipoprotein E epsilon-4 polymorphism is associated with younger age at referral to a lipidology clinic and a poorer response to lipid-lowering therapy

BACKGROUND: The risk of coronary heart disease (CHD) is related to environmental factors and genetic variants. Apolipoprotein E (apoE) polymorphisms are heritable determinants of total and low-density lipoprotein cholesterol, with some authors suggesting an association between the ε4 allele and CHD....

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Bibliographische Detailangaben
Hauptverfasser: Baptista, Rui, Rebelo, Marta, Decq-Mota, Joana, Dias, Patrícia, Monteiro, Pedro, Providência, Luís A, Silva, José M
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078893/
https://ncbi.nlm.nih.gov/pubmed/21450082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-10-48
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