Sequential requirements for the GTPase domain of the mitofusin Fzo1 and the ubiquitin ligase SCF(Mdm30) in mitochondrial outer membrane fusion

The ability of cells to respire requires that mitochondria undergo fusion and fission of their outer and inner membranes. The means by which levels of fusion ‘machinery’ components are regulated and the molecular details of how fusion occurs are largely unknown. In Saccharomyces cerevisiae, a centra...

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Main Authors: Cohen, Mickael M., Amiott, Elizabeth A., Day, Adam R., Leboucher, Guillaume P., Pryce, Erin N., Glickman, Michael H., McCaffery, J. Michael, Shaw, Janet M., Weissman, Allan M.
Formato: Artigo
Idioma:Inglês
Publicado: Company of Biologists 2011
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078809/
https://ncbi.nlm.nih.gov/pubmed/21502136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.079293
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