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The Mitochondrial Permeability Transition Pore Regulates Nitric Oxide-Mediated Apoptosis of Neurons Induced by Target Deprivation

Ablation of mouse occipital cortex induces precisely timed and uniform p53-modulated and Bax-dependent apoptosis of thalamocortical projection neurons in the dorsal lateral geniculate nucleus (LGN) by 7 d after lesion. We tested the hypothesis that this neuronal apoptosis is initiated by oxidative s...

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Autors principals: Martin, Lee J., Adams, Neal A., Pan, Yan, Price, Ann, Wong, Margaret
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078575/
https://ncbi.nlm.nih.gov/pubmed/21209222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2225-10.2011
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