Inhibition of Na(+)/H(+) Exchanger Isoform 1 Is Neuroprotective in Neonatal Hypoxic Ischemic Brain Injury

We investigated the role of Na(+)/H(+) exchanger isoform 1 (NHE-1) in neonatal hypoxia/ischemia (HI). HI was induced by unilateral ligation of the left common carotid artery in postnatal day 9 (P9) mice, and subsequent exposure of animals to 8% O(2) for 55 min. A pre/posttreatment group received a s...

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Detalhes bibliográficos
Main Authors: Cengiz, Pelin, Kleman, Neil, Uluc, Kutluay, Kendigelen, Pinar, Hagemann, Tracy, Akture, Erinc, Messing, Albee, Ferrazzano, Peter, Sun, Dandan
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Forum Original Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078509/
https://ncbi.nlm.nih.gov/pubmed/20712402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3468
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