Pathophysiologically Relevant Levels of Hydrogen Peroxide Induce Glutamate-Independent Neurodegeneration That Involves Activation of Transient Receptor Potential Melastatin 7 Channels

Stroke/brain ischemia is a leading cause of death and long-term disabilities. Increased oxidative stress plays an important role in the pathology of brain ischemia. Hydrogen peroxide (H(2)O(2)) is a major oxidant known to cause neuronal injury; however, the detailed mechanism remains unclear. Previo...

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Bibliografski detalji
Glavni autori: Coombes, Emily, Jiang, Jie, Chu, Xiang-Ping, Inoue, Koichi, Seeds, Joshua, Branigan, Deborah, Simon, Roger P., Xiong, Zhi-Gang
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2011
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Forum Original Research Communications
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078500/
https://ncbi.nlm.nih.gov/pubmed/20812867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3549
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