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Activation of cAMP-dependent protein kinase alters the chromatin structure of the urokinase-type plasminogen activator gene promoter.

In LLC-PK1 cells, the urokinase-type plasminogen activator (uPA) gene is induced by two of the major signal transduction pathways, the protein kinase C (PKC) and the cAMP-dependent protein kinase (PKA) pathways. We have analyzed the chromatin structure of 26 kb of the uPA gene locus and have shown t...

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Detalles Bibliográficos
Main Authors: Lee, J S, Catanzariti, L, Hemmings, B A, Kiefer, B, Nagamine, Y
Formato: Artigo
Idioma:Inglês
Publicado: 1994
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC307845/
https://ncbi.nlm.nih.gov/pubmed/8127705
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