KSR1 Is Overexpressed in Endometrial Carcinoma and Regulates Proliferation and TRAIL-Induced Apoptosis by Modulating FLIP Levels

The Raf/MEK/extracellular signal-regulated kinase (ERK) pathway participates in many processes altered in development and progression of cancer in human beings such as proliferation, transformation, differentiation, and apoptosis. Kinase suppressor of Ras 1 (KSR1) can interact with various kinases o...

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Main Authors: Llobet, David, Eritja, Nuria, Domingo, Monica, Bergada, Laura, Mirantes, Cristina, Santacana, Maria, Pallares, Judit, Macià, Anna, Yeramian, Andree, Encinas, Mario, Moreno-Bueno, Gema, Palacios, Jose, Lewis, Robert E., Matias-Guiu, Xavier, Dolcet, Xavi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2011
Teme:
Regular Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078440/
https://ncbi.nlm.nih.gov/pubmed/21435442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.041
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