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Oxidation of NADPH on Kvβ1 inhibits ball-and-chain type inactivation by restraining the chain
The Kv1 family voltage-dependent K(+) channels assemble with cytosolic β subunits (Kvβ), which are composed of a flexible N terminus followed by a structured core domain. The N terminus of certain Kvβs inactivates the channel by blocking the ion conduction pore, and the core domain is a functional e...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078402/ https://ncbi.nlm.nih.gov/pubmed/21436029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100316108 |
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