AMP-activated protein kinase (AMPK) activity is not required for neuronal development but regulates axogenesis during metabolic stress

Mammalian brain connectivity requires the coordinated production and migration of billions of neurons and the formation of axons and dendrites. The LKB1/Par4 kinase is required for axon formation during cortical development in vivo partially through its ability to activate SAD-A/B kinases. LKB1 is a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Williams, Tyisha, Courchet, Julien, Viollet, Benoit, Brenman, Jay E., Polleux, Franck
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2011
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078367/
https://ncbi.nlm.nih.gov/pubmed/21436046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013660108
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