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AMP-activated protein kinase (AMPK) activity is not required for neuronal development but regulates axogenesis during metabolic stress

Mammalian brain connectivity requires the coordinated production and migration of billions of neurons and the formation of axons and dendrites. The LKB1/Par4 kinase is required for axon formation during cortical development in vivo partially through its ability to activate SAD-A/B kinases. LKB1 is a...

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Hlavní autoři: Williams, Tyisha, Courchet, Julien, Viollet, Benoit, Brenman, Jay E., Polleux, Franck
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078367/
https://ncbi.nlm.nih.gov/pubmed/21436046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013660108
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