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Roles of the SH2 and SH3 domains in the regulation of neuronal Src kinase functions
Previous studies demonstrate that intradomain interactions of Src family kinases (SFKs), stabilized by binding of the phosphorylated C-tail to the SH2 domain and/or the binding of the SH2-kinase linker to the SH3 domain, lock the molecules in a closed conformation, disrupt the kinase active site and...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078127/ https://ncbi.nlm.nih.gov/pubmed/21199370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2010.07985.x |
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