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Gfer inhibits Jab1-mediated degradation of p27(kip1) to restrict proliferation of hematopoietic stem cells
Growth factor erv1-like (Gfer) is an evolutionarily conserved sulfhydryl oxidase that is enriched in embryonic and adult stem cells and plays an essential prosurvival role in pluripotent embryonic stem cells. Here we show that knockdown (KD) of Gfer in hematopoietic stem cells (HSCs) compromises the...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078070/ https://ncbi.nlm.nih.gov/pubmed/21346186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-08-0723 |
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