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The Ndc80 complex uses a tripartite attachment point to couple microtubule depolymerization to chromosome movement
In kinetochores, the Ndc80 complex couples the energy in a depolymerizing microtubule to perform the work of moving chromosomes. The complex directly binds microtubules using an unstructured, positively charged N-terminal tail located on Hec1/Ndc80. Hec1/Ndc80 also contains a calponin homology domai...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Cell Biology
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078066/ https://ncbi.nlm.nih.gov/pubmed/21325630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-07-0626 |
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