SUPPRESSION OF THE NITRIC OXIDE PATHWAY IN METASTATIC RENAL CELL CARCINOMA PATIENTS RECEIVING VEGF-SIGNALING INHIBITORS

Therapies that target the vascular endothelial growth factor (VEGF) pathway cause hypertension but the mechanism remains unknown. This cross-sectional study tested the hypothesis that VEGF inhibition causes hypertension by suppressing VEGF-mediated vasodilatory pathways. Urine was collected from 80...

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Detalhes bibliográficos
Main Authors: Robinson, Emily S., Khankin, Eliyahu V., Choueiri, Toni K., Dhawan, Mallika D., Rogers, Miranda J., Karumanchi, S. Ananth, Humphreys, Benjamin D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078049/
https://ncbi.nlm.nih.gov/pubmed/20956731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.110.160481
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