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Inhibition of the M. tuberculosis 3β-Hydroxysteroid Dehydrogenase by Azasteroids
[Image: see text] The cholesterol metabolism pathway in Mycobacterium tuberculosis (M. tb) is a potential source of energy as well as secondary metabolite production that is important for survival of M. tb in the host macrophage. Oxidation and isomerization of 3β-hydroxysterols to 4-en-3-ones is req...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077731/ https://ncbi.nlm.nih.gov/pubmed/21439822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.03.004 |
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