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Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids
Here we report that Cyclooxygenase-2 (COX-2) mediates the formation of electrophilic fatty acid oxo-derivatives (EFOXs) from the omega-3 fatty acids (ω-3 FA) docosahexaenoic, docosapentaenoic and docosatetraenoic acid. EFOXs produced by activated macrophages were discovered by a mass spectrometry-ba...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077712/ https://ncbi.nlm.nih.gov/pubmed/20436486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.367 |
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