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Double Anti-angiogenic and Anti-inflammatory Protein Valpha Targeting VEGF-A and TNF-α in Retinopathy and Psoriasis

Pathological angiogenesis usually involves disrupted vascular integrity, vascular leakage, and infiltration of inflammatory cells, which are governed mainly by VEGF-A and TNF-α. Although many inhibitors targeting either VEGF-A or TNF-α have been developed, there is no single inhibitor molecule that...

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Bibliografske podrobnosti
Main Authors: Jung, Keehoon, Lee, Donghun, Lim, Hye Song, Lee, Sang-Il, Kim, Yeon Jung, Lee, Gyun Min, Kim, Sun Chang, Koh, Gou Young
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077640/
https://ncbi.nlm.nih.gov/pubmed/21345791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.228130
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