Kir4.1 Channel Expression Is Essential for Parietal Cell Control of Acid Secretion

Kir4.1 channels were found to colocalize with the H(+)/K(+)-ATPase throughout the parietal cell (PC) acid secretory cycle. This study was undertaken to explore their functional role. Acid secretory rates, electrophysiological parameters, PC ultrastructure, and gene and protein expression were determ...

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Autori principali: Song, Penghong, Groos, Stephanie, Riederer, Brigitte, Feng, Zhe, Krabbenhöft, Anja, Manns, Michael P., Smolka, Adam, Hagen, Susan J., Neusch, Clemens, Seidler, Ursula
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077613/
https://ncbi.nlm.nih.gov/pubmed/21367857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.151191
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