A Spring-loaded Release Mechanism Regulates Domain Movement and Catalysis in Phosphoglycerate Kinase

Phosphoglycerate kinase (PGK) is the enzyme responsible for the first ATP-generating step of glycolysis and has been implicated extensively in oncogenesis and its development. Solution small angle x-ray scattering (SAXS) data, in combination with crystal structures of the enzyme in complex with subs...

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Detalhes bibliográficos
Main Authors: Zerrad, Louiza, Merli, Angelo, Schröder, Gunnar F., Varga, Andrea, Gráczer, Éva, Pernot, Petra, Round, Adam, Vas, Mária, Bowler, Matthew W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077604/
https://ncbi.nlm.nih.gov/pubmed/21349853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.206813
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