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Chronic High-Fat Diet Drives Postnatal Epigenetic Regulation of μ-Opioid Receptor in the Brain

Opioid system dysregulation has been observed in both genetic and high-fat diet (HFD)-induced models of obesity. An understanding of the molecular mechanisms of MOR transcriptional regulation, particularly within an in vivo context, is lacking. Using a diet-induced model of obesity (DIO), mice were...

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Detalhes bibliográficos
Main Authors: Vucetic, Zivjena, Kimmel, Jessica, Reyes, Teresa M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077442/
https://ncbi.nlm.nih.gov/pubmed/21326195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.4
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