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Oligonucleotide duplexes containing 2'-amino-2'-deoxycytidines: thermal stability and chemical reactivity.

Thermal stabilities of oligonucleotides containing 2'-amino-2'-deoxycytidines were determined and compared to those of the unmodified oligonucleotides. The presence of the 2'-aminonucleoside destabilized duplexes in a RNA as well as a DNA context at pH 7 as well as at pH 5. The pKa of...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Aurup, H, Tuschl, T, Benseler, F, Ludwig, J, Eckstein, F
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 1994
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307740/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8127651/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.1.20
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