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Tissue-Autonomous Function of Drosophila Seipin in Preventing Ectopic Lipid Droplet Formation

Obesity is characterized by accumulation of excess body fat, while lipodystrophy is characterized by loss or absence of body fat. Despite their opposite phenotypes, these two conditions both cause ectopic lipid storage in non-adipose tissues, leading to lipotoxicity, which has health-threatening con...

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Detalhes bibliográficos
Main Authors: Tian, Yuan, Bi, Junfeng, Shui, Guanghou, Liu, Zhonghua, Xiang, Yanhui, Liu, Yuan, Wenk, Markus R., Yang, Hongyuan, Huang, Xun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077376/
https://ncbi.nlm.nih.gov/pubmed/21533227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001364
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