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Evaluation of LAGE-1 and NY-ESO-1 expression in multiple myeloma patients to explore possible benefits of their homology for immunotherapy

Due to the high homology between the LAGE-1 and NY-ESO-1 proteins, we hypothesized that an anti-NY-ESO-1 vaccine might elicit LAGE-1 immunity and hence may be effective in multiple myeloma (MM) patients with LAGE-1-positive/NY-ESO-1-negative tumors. Therefore, we set out to evaluate LAGE-1 and NY-ES...

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Hlavní autoři: de Carvalho, Fabricio, Vettore, Andre L., Inaoka, Riguel J., Karia, Bruno, Andrade, Valéria C. C., Gnjatic, Sacha, Jungbluth, Achim A., Colleoni, Gisele W. B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Academy of Cancer Immunology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077292/
https://ncbi.nlm.nih.gov/pubmed/21247062
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