Inhaled nitrite reverses hemolysis-induced pulmonary vasoconstriction in newborn lambs without blood participation: Blood- Conversion of inhaled nitrite to NO

BACKGROUND: Nitrite can be converted to nitric oxide (NO) by a number of different biochemical pathways. In newborn lambs an aerosol of inhaled nitrite has been found to reduce pulmonary blood pressure, possibly acting via conversion to NO by reaction with intraerythrocytic deoxyhemoglobin. If so, t...

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Bibliographische Detailangaben
Hauptverfasser: Blood, Arlin B., Schroeder, Hobe J., Terry, Michael H., Merrill-Henry, Jeanette, Bragg, Shannon L., Vrancken, Kurt, Liu, Taiming, Herring, Jason L., Sowers, Lawrence C., Wilson, Sean M., Power, Gordon G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077283/
https://ncbi.nlm.nih.gov/pubmed/21282501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.110.001073
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