Effects of Direct- and Indirect-Acting Serotonin Receptor Agonists on the Antinociceptive and Discriminative Stimulus Effects of Morphine in Rhesus Monkeys

Serotonergic (5-HT) systems modulate pain, and drugs acting on 5-HT systems are used with opioids to treat pain. This study examined the effects of 5-HT receptor agonists on the antinociceptive and discriminative stimulus effects of morphine in monkeys. Morphine increased tail-withdrawal latency in...

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Main Authors: Li, Jun-Xu, Koek, Wouter, Rice, Kenner C, France, Charles P
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2011
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077263/
https://ncbi.nlm.nih.gov/pubmed/21209613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.232
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