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Hepatitis C Virus NS2 Protein Triggers Endoplasmic Reticulum Stress and Suppresses its Own Viral Replication

BACKGROUND & AIMS: We previously reported that the NS2 protein of hepatitis C virus (HCV) inhibits the expression of reporter genes driven by a variety of cellular and viral promoters. The aim of the study was to determine whether the broad transcriptional repression is caused by endoplasmic ret...

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Detalhes bibliográficos
Main Authors: von dem Bussche, Annette, Machida, Raiki, Li, Ke, Loevinsohn, Gideon, Khander, Amrin, Wang, Jianguo, Wakita, Takaji, Wands, Jack R., Li, Jisu
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077220/
https://ncbi.nlm.nih.gov/pubmed/20801537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2010.05.022
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