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CX3CR1 in Microglia Regulates Brain Amyloid Deposition through Selective Protofibrillar Amyloid-β Phagocytosis

In Alzheimer's disease (AD), amyloid-β (Aβ) deposits are frequently surrounded by activated microglia but the precise role of these cells in disease progression remains unclear. The chemokine receptor CX3CR1 is selectively expressed in microglia and is thought to modulate their activity. To stu...

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Detaylı Bibliyografya
Asıl Yazarlar: Liu, Zhiqiang, Condello, Carlo, Schain, Aaron, Harb, Roa, Grutzendler, Jaime
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077120/
https://ncbi.nlm.nih.gov/pubmed/21159979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4403-10.2010
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