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Aldosterone synthesis in the brain contributes to Dahl salt-sensitive rat hypertension

The enzymes required for aldosterone synthesis from cholesterol are expressed in rat and human brains. The hypertension of Dahl salt-sensitive (SS) rats is mitigated by the intracerebroventricular (i.c.v.) infusion of antagonists of the mineralocorticoid receptor (MR) and downstream effectors of min...

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Autori principali: Gomez-Sanchez, Elise P., Gomez-Sanchez, Clara M., Plonczynski, Maria, Gomez-Sanchez, Celso E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077084/
https://ncbi.nlm.nih.gov/pubmed/19837774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2009.048900
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