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Role of Tissue Factor in Venous Thrombosis

Venous thromboembolism (VTE) is a leading cause of morbidity and mortality worldwide. However, the mechanisms by which clots are formed in the deep veins have not been determined. Tissue factor (TF) is the primary initiator of the coagulation cascade and is essential for hemostasis. Under pathologic...

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Bibliographic Details
Main Authors: Manly, David A., Boles, Jeremiah, Mackman, Nigel
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076951/
https://ncbi.nlm.nih.gov/pubmed/20690821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-physiol-042210-121137
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