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A Peptidomics Strategy to Elucidate the Proteolytic Pathways that Inactivate Peptide Hormones

Proteolysis plays a key role in regulating the levels and activity of peptide hormones. Characterization of the proteolytic pathways that cleave peptide hormones is of basic interest and can, in some cases, spur the development of novel therapeutics. The lack, however, of an efficient approach to id...

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Detalhes bibliográficos
Main Authors: Tinoco, Arthur D., Kim, Yun-Gon, Tagore, Debarati M., Wiwczar, Jessica, Lane, William S., Danial, Nika N., Saghatelian, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076939/
https://ncbi.nlm.nih.gov/pubmed/21299233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2000033
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