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A Peptidomics Strategy to Elucidate the Proteolytic Pathways that Inactivate Peptide Hormones

Proteolysis plays a key role in regulating the levels and activity of peptide hormones. Characterization of the proteolytic pathways that cleave peptide hormones is of basic interest and can, in some cases, spur the development of novel therapeutics. The lack, however, of an efficient approach to id...

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Autori principali: Tinoco, Arthur D., Kim, Yun-Gon, Tagore, Debarati M., Wiwczar, Jessica, Lane, William S., Danial, Nika N., Saghatelian, Alan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076939/
https://ncbi.nlm.nih.gov/pubmed/21299233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2000033
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