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Electrostatic influences of charged inner pore residues on the conductance and gating of small conductance Ca(2+) activated K(+) channels

SK channels underlie important physiological functions by linking calcium signaling with neuronal excitability. Potassium currents through SK channels demonstrate inward rectification, which further reduces their small outward conductance. Although it has been generally attributed to block of outwar...

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Detalhes bibliográficos
Main Authors: Li, Weiyan, Aldrich, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076840/
https://ncbi.nlm.nih.gov/pubmed/21422289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103090108
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