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Electrostatic influences of charged inner pore residues on the conductance and gating of small conductance Ca(2+) activated K(+) channels
SK channels underlie important physiological functions by linking calcium signaling with neuronal excitability. Potassium currents through SK channels demonstrate inward rectification, which further reduces their small outward conductance. Although it has been generally attributed to block of outwar...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076840/ https://ncbi.nlm.nih.gov/pubmed/21422289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103090108 |
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