TNF is required for the induction but not the maintenance of compression-induced BME signals in murine tail vertebrae: limitations of anti-TNF therapy for degenerative disc disease

While bone marrow edema (BME) is diagnostic of spondyloarthropathy, its nature remains poorly understood. In contrast, BME in ankylosing spondylitis is caused by TNF-induced vascular and cellular changes. To investigate the relationship between chronic compression and TNF signaling in compression in...

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Detaylı Bibliyografya
Asıl Yazarlar: Papuga, M. Owen, Kwok, Edmund, You, Zhigang, Rubery, Paul T., Dougherty, Paul E., Pryhuber, Gloria, Beck, Christopher A., Hilton, Matthew J., Awad, Hani A., Schwarz, Edward M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076794/
https://ncbi.nlm.nih.gov/pubmed/21445993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.21370
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