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Length heteroplasmies in human mitochondrial DNA control regions and breast cancer risk

It has been proposed that the presence of heteroplasmy in the hypervariable (HV) regions of the mitochondrial DNA (mtDNA) may be an indicator of mitochondrial genome instability, mtDNA dysfunction, and, thus, may be associated with increased cancer risk. However, whether heteroplasmy in the HV regio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhao, Hua, Shen, Jie, Medico, Leonard, Platek, Mary, Ambrosone, Christine B
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076767/
https://ncbi.nlm.nih.gov/pubmed/21537390
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