Using In silico LD clumping and meta-analysis of genome-wide datasets as a complementary tool to investigate and validate new candidate biomarkers in Alzheimer's disease

Despite the recent wealth of genome-wide association studies, insufficient power may explain why much of the heritable contribution to common diseases remains hidden. As different SNP panels are genotyped by commercial chips, increasing study power through meta-analysis is made problematic. To addre...

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Bibliographic Details
Main Authors: Medway, Christopher, Shi, Hui, Bullock, James, Black, Holly, Brown, Kristelle, Vafadar-isfahani, Baharak, Matharoo-ball, Balwir, Ball, Graham, Rees, Robert, Kalsheker, Noor, Morgan, Kevin
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2010
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076759/
https://ncbi.nlm.nih.gov/pubmed/21537386
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