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Association between CYP7A1 and the risk of proximal colon cancer in Japanese

Bile acids have long been implicated in the etiology of colorectal carcinogenesis by their genotoxicity as well as cytotoxicity. Cholesterol 7-alfa-hydroxylase (CYP7A1) is the rate-limiting enzyme that converts cholesterol into cholesterol 7-alfa-hydroxycholesterol in the first step of the classical...

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Detalhes bibliográficos
Main Authors: Ito, Hidemi, Matsuo, Keitaro, Hosono, Satoyo, Watanabe, Miki, Kawase, Takakazu, Suzuki, Takeshi, Hirai, Takashi, Yatabe, Yasushi, Tanaka, Hideo, Tajima, Kazuo
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076754/
https://ncbi.nlm.nih.gov/pubmed/21537451
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