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Reaction of the Butter Flavorant Diacetyl (2,3-Butanedione) with N-α-Acetylarginine: A Model for Epitope Formation with Pulmonary Proteins in the Etiology of Obliterative Bronchiolitis

The butter flavorant diacetyl (2,3-butanedione) is implicated in causing obliterative bronchiolitis in microwave popcorn plant workers. Because diacetyl modifies arginine residues, an immunological basis for its toxicity is under investigation. Reaction products of diacetyl with N-α-acetylarginine (...

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Detalhes bibliográficos
Main Authors: Mathews, James M., Watson, Scott L., Snyder, Rodney W., Burgess, Jason P., Morgan, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076710/
https://ncbi.nlm.nih.gov/pubmed/21077678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jf103251w
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