The novel atherosclerosis locus at 10q11 regulates plasma CXCL12 levels

AIMS: Two single-nucleotide polymorphisms (SNPs), rs1746048 and rs501120, from genome wide association studies of coronary artery disease (CAD) map to chromosome 10q11 ∼80 kb downstream of chemokine CXCL12. Therefore, we examined the relationship between these two SNPs and plasma CXCL12 levels. METH...

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Main Authors: Mehta, Nehal N., Li, Mingyao, William, Dilusha, Khera, Amit V., DerOhannessian, Stephanie, Qu, Liming, Ferguson, Jane F., McLaughlin, Catherine, Shaikh, Lalarukh Haris, Shah, Rhia, Patel, Parth N., Bradfield, Jonathan P., He, Jing, Stylianou, Ioannis M., Hakonarson, Hakon, Rader, Daniel J., Reilly, Muredach P.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076669/
https://ncbi.nlm.nih.gov/pubmed/21415067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehr091
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