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Aldehyde dehydrogenase 2 (ALDH2) rescues myocardial ischaemia/reperfusion injury: role of autophagy paradox and toxic aldehyde
AIMS: The present study was designed to examine the mechanism involved in mitochondrial aldehyde dehydrogenase (ALDH2)-induced cardioprotection against ischaemia/reperfusion (I/R) injury with a focus on autophagy. METHODS: Wild-type (WT), ALDH2 overexpression, and knockout (KO) mice (n = 4–6 for eac...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Oxford University Press
2011
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076664/ https://ncbi.nlm.nih.gov/pubmed/20705694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehq253 |
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